CHEM& 131: Introduction to Organic/Biochemistry

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Class Program

Chemistry

Credits

Clinical Hours None

Weekly Contact Hours

Course ID

091532

Meets Degree Requirements For

Natural Science with Lab

Description

Introductory organic and biochemistry satisfying allied health and transfer agriculture program requirements. A study of the principal functional groups of organic chemistry, nomenclature, physical properties, basic reactions, and their applications to living systems. Covers the principal classes of biomolecules (proteins, carbohydrates, lipids and nucleic acids). Includes laboratory.

Prerequisites

CHEM& 121 or equivalent

Course Learning Outcomes

Readily identify the principal functional groups of organic chemistry and relate them to physical and chemical properties of a given compound

Apply the rules of organic nomenclature organic nomenclature to communicate the structure of a given molecule, and distinguish it from similarly structured or oriented molecules

Explain expected reactions of organic and biological molecules given environment/reaction conditions and apply this understanding to physiologic phenomena

Apply an understanding of protein, carbohydrate, lipid, and nucleic acid structure and function to metabolism and cellular phenomenon

Apply a functional group organic chemistry approach towards biological macromolecules to better understand the genesis of these molecules and their overall disposition in the body

Use an understanding of cellular molecular structure and function to explain neurological, hormonal, and genetic functions in living systems

Manipulate laboratory equipment and reagents to investigate chemical changes specific to organic/bioorganic systems through application of the scientific method with a partner or as part of a small group

Core Topics

Definition of organic and biochemistry, organic nomenclature, representing organic structures, geometric considerations, conformational flexibility, and isomerism. Alkanes
Lab: Check in, Making of a Hand Cream
Alkenes and aromatic systems – structure, nomenclature, physical properties, reactivities and pertinent examples
Lab: Structural formulas/Organic functional groups (model building)
Alcohols, ethers, and analogs – structure, nomenclature, physical properties, reactivities and pertinent examples. Amines - structure, nomenclature, physical properties, reactivities and prevalence in alkaloid drug molecules.
Lab: Organic nomenclature (model building and identification)
Compounds containing the carbonyl – aldehydes and ketones: structure, nomenclature, physical properties, reactivities and pertinent examples, the importance of oxidation and reduction in organic and biochemistry
Lab: Representative reactions for several organic functional groups/families
Compounds containing the carbonyl – acids and acid derivatives, including esters, amides, and phosphoesters: structure, nomenclature, physical properties, reactivities and pertinent examples
Lab: Synthesis of esters and aspirin
Proteins and Enzymes – naming, structure, function, and uses
Lab: Biochemistry pot luck
Carbohydrates – naming, structure, reactivity, biologic function, and uses. Important monosaccharides, disaccharides, and polysaccharides
Lab: Carbohydrates and lipids
Lipids – naming, physical properties, reactivities, emphasizing triglycerides, complex lipids of the cellular membrane, steroids, and lipid transport
Lab: Carbohydrates and lipids continued
Nucleic acids – variety, structure, function, and role in information transfer. Replication, transcription, and translation
Lab: Soap
Regulation of gene expression and/or carbohydrate, lipid, and protein metabolism/energy generation
Lab: Check out