CHEM& 262: Organic Chemistry II

Class Program
Weekly Contact Hours
Course ID
Meets Degree Requirements For
Natural Science with Lab

The second of a three-quarter sequence in organic chemistry for university transfer, intended primarily for science majors and those fulfilling requirements for professional health science careers such as medicine, dentistry and pharmacy. CHEM& 262 furthers the development of the properties, transformations and identification of organic molecules. Lab included.

Grading Basis

Course Learning Outcomes

Core Topics

In Brief:


  1. Radical reactions
  2. Alcohols and ethers: properties and nomenclature of alcohols and ethers, synthesis and reactions of alcohols, synthesis and reactions of ethers
  3. Organic redox reactions, organometallic compounds, Grignard reactions
  4. Conjugated unsaturated systems: resonance, 1,4 addition, Diels-Alder reaction
  5. Aromatic compounds: benzene, electrophilic aromatic substitution, Friedel-Crafts and related reactions
  6. Aldehydes and ketones: additions to the carbonyl group
  7. Analytical techniques: Nuclear magnetic resonance spectrometry, mass spectrometry, infrared and ultraviolet-visible spectroscopy further developed
  8. HPLC and other chromatographic separation/sample purity techniques further developed

In Detail:


  1. Interpret a 13C nmr spectrum in terms of carbon chemical shift and number of attached protons.
  2. Identify compounds based on their 13C nmr spectra.
  3. Identify compounds based on their two dimensional nmr spectra.
  4. Explain the function of modern multi-dimensional and multi-sector mass spectrometers.
  5. Define and utilize parent, daughter, and neutral loss spectra in identifying compounds in complex mixtures
  6. Write detailed reaction mechanisms for a variety of free radical reactions, including radical polymerization reactions.
  7. Explain anti-Markovnikov addition.
  8. Name alcohols, ethers, organohalogen compounds, aromatic compounds, aldehydes, and ketones according to IUPAC rules.
  9. Explain the physical properties of alcohols, ethers, aldehydes, ketones, and aromatic compounds.
  10. Write equations for the synthesis of alcohols from alkenes using acid catalyzed hydration, oxymercuration/demercuration, and hydroboration/oxidation.
  11. Write equations for reactions involving alcohols, including acid/base reactions, the formation and use of mesylates and tosylates, and their conversion into alkyl halides.
  12. Write equations for the synthesis of ethers and the reactions of ethers.
  13. Analyze the structure and reactivity of epoxides.
  14. Explain the use of crown ethers as phase transfer catalysts.
  15. Identify organic redox reactions.
  16. Generate organometallic reagents, understand their key features and unique properties, and execute the synthesis of a variety of compounds from them.
  17. Use resonance to explain the stability of allyl radicals and cations.
  18. Know the rules of resonance and utilize them to explain the behavior of various  systems
  19. Explain the bonding in conjugated unsaturated systems.
  20. Write equations for 1,4-addition reactions of conjugated dienes.
  21. Write equations for the synthesis of cyclic compounds using Diels-Alder reactions.
  22. Use uv-vis spectra to aid in compound identification.
  23. *******
  24. Explain   *, n  * and related transitions
  25. Explain the bonding in benzene and other aromatic compounds.
  26. Describe the orbital basis for Hückels rule
  27. Utilize Hückels rule to predict when compounds will be aromatic.
  28. Write detailed reaction mechanisms for electrophilic aromatic substitution reactions.
  29. Write equations for the synthesis of a variety of compounds using electrophilic aromatic substitution reactions.
  30. Using a variety of reactions, write equations for the synthesis of aldehydes and ketones.
  31. Write detailed reaction mechanisms for reactions involving addition to the carbonyl group.
  32. Write equations for the synthesis of a variety of compounds using addition to carbonyl groups.
  33. Practice standard laboratory safety precautions.
  34. Skillfully communicate the results of laboratory work.
  35. Design and carry out an experimental procedure to solve a specific problem.
  36. Isolate and characterize natural products.
  37. Synthesize organic compounds.
  38. Obtain NMR, GC/MS, HPLC, FT-IR and other data to establish sample purity and compound identity
  39. Use chemical reference material appropriately.
  40. Work effectively in groups.